Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology. The finding, if it continues to hold true in nonhuman primates and clinicalContinuar Leyendo
By uncovering the subtle difference between two varieties of a protein, researchers from the Perelman School of Medicine at the University of Pennsylvania may have discovered how to eliminate the risk of weight gain from a certain type of diabetes medication. Through this, it’s possible that more patients with diabetesContinuar Leyendo
Tiny structures called nanoparticles can be used to carry substances to certain parts of the body — for example, to deliver a chemotherapy drug to a tumor. Although such «nanomedicine» offered hope for improving cancer therapeutics, the survival benefits of clinically approved nanomedicines are often modest when compared with conventionalContinuar Leyendo
Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery. Hamilton, March 13, 2022.- Developing new strategies and vaccine technologiesContinuar Leyendo
Irish and German scientists have just identified how specific immune cells can work together in fat to cause inflammation that leads to weight gain and obesity. Their work pinpoints new avenues to exploit the regulation of that inflammation in fat tissue, thereby suggesting new ways to manage obesity [Wednesday 9thContinuar Leyendo
Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments. New Yor, March 06, 2022.- The study, published Feb. 8 in Nature Communications, details the precise molecularContinuar Leyendo
Take a cell-deep tour of a brain afflicted with Alzheimer’s disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures. New York, March 06, 2022.-Continuar Leyendo
Only one currently authorized antibody treatment retains its activity against all Omicron subvariants, according to new research by scientists at Columbia University and the University of Hong Kong. The study also shows that the effectiveness of mRNA vaccines is reduced against all three subvariants of Omicron. New York, March 04,Continuar Leyendo
The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection model, scientists from the Institut Pasteur and Inserm discovered that innate effector cells — group 3 innate lymphoid cells — act not onlyContinuar Leyendo
Nearly 90 percent of COVID-19 patients who qualified for, but did not receive, ECMO (extracorporeal membrane oxygenation) due to a shortage of resources during the height of the pandemic died in the hospital, despite being young with few other health issues, according to a study published in the American JournalContinuar Leyendo
