A novel system to control protein aggregation in a model of Parkinson’s disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9 in the open-access journal PLOS Biology by Abid Oueslati of Laval University, Quebec, Canada, and colleagues. Initial resultsContinuar Leyendo
Alzheimer’s disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau. A study by researchers at Washington University School of Medicine in St. Louis has shown that targeting astrocytes — an inflammatory cell in theContinuar Leyendo
Children previously infected with COVID-19 develop natural circulating antibodies that last for at least seven months, according to a new study led by researchers at UTHealth Houston. The study was published today in Pediatrics. Houston, March 20, 2022.- Researchers examined data from 218 children across the state of Texas betweenContinuar Leyendo
While many people in wealthier countries have been vaccinated against Covid-19, there is still a need for vaccination in much of the world. A new vaccine developed at MIT and Beth Israel Deaconess Medical Center may aid in those efforts, offering an inexpensive, easy-to-store, and effective alternative to RNA vaccines.Continuar Leyendo
Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology. The finding, if it continues to hold true in nonhuman primates and clinicalContinuar Leyendo
By uncovering the subtle difference between two varieties of a protein, researchers from the Perelman School of Medicine at the University of Pennsylvania may have discovered how to eliminate the risk of weight gain from a certain type of diabetes medication. Through this, it’s possible that more patients with diabetesContinuar Leyendo
Tiny structures called nanoparticles can be used to carry substances to certain parts of the body — for example, to deliver a chemotherapy drug to a tumor. Although such «nanomedicine» offered hope for improving cancer therapeutics, the survival benefits of clinically approved nanomedicines are often modest when compared with conventionalContinuar Leyendo
Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery. Hamilton, March 13, 2022.- Developing new strategies and vaccine technologiesContinuar Leyendo
Irish and German scientists have just identified how specific immune cells can work together in fat to cause inflammation that leads to weight gain and obesity. Their work pinpoints new avenues to exploit the regulation of that inflammation in fat tissue, thereby suggesting new ways to manage obesity [Wednesday 9thContinuar Leyendo
Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments. New Yor, March 06, 2022.- The study, published Feb. 8 in Nature Communications, details the precise molecularContinuar Leyendo
