Scientists at the Max Planck Institute for Medical Research in Heidelberg and their collaborators at the Max Planck Bristol Center for Minimal Biology at the University of Bristol have developed a new approach to study Sars-CoV-2. For systematic and standardized research of Sars-CoV-2 they built minimalistic synthetic virus particles whereContinuar Leyendo
T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer, with lower T-cell responses observed in patients with blood cancers, according to results from a study published in Cancer Discovery, a journal of theContinuar Leyendo
Zurich, Feb 18, 2022.- Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and the most common cause of neurological impairment in young adults. In MS, the patient’s own immune system attacks the brain and spinal cord, resulting in cumulative neurological deficits such as damaged sight,Continuar Leyendo
A number of existing strains of SARS-CoV-2, as well as other future variants that could arise, have the potential to escape the immune system’s cytotoxic T cell response in some portion of the population. That’s the conclusion of a new modeling study publishing Feb. 10 in PLOS Computational Biology byContinuar Leyendo
Vitamin D is most often recognized for its role in bone health, but low levels of the supplement have been associated with a range of autoimmune, cardiovascular, and infectious diseases. Early on in the pandemic health officials began to encourage people to take vitamin D, as it plays a roleContinuar Leyendo
Researchers have discovered a mechanism that may explain why COVID-19 patients lose their sense of smell. New York, Feb 04, 2022.- Published online February 2 in the journal Cell, the new study found that infection with the pandemic virus, SARS-CoV-2, indirectly dials down the action of olfactory receptors (OR), proteinsContinuar Leyendo
A new study by researchers at Yale Cancer Center shows inhibition of the CECR2 gene prevents triple-negative breast cancer from advancing or metastasizing. The discovery is an early step in finding new therapeutics for triple-negative breast cancer (TNBC), one of the most difficult disease sub-types to treat. The findings areContinuar Leyendo
Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and prolonging survival in animal models, a research team at Massachusetts General Hospital (MGH) has discovered. The combined strategy, described in ACS Nano, usesContinuar Leyendo
In cancer research, it has long been known that lactic acid, or lactate, is produced in large quantities by cancer cells and that this lactic acid disrupts our defence against tumours. Until now, however, we did not know exactly how this happens. Prof Jo Van Ginderachter, immunologist and cancer researcherContinuar Leyendo
A Zika virus vaccine candidate is effective at preventing the Zika virus passing from mother to fetus in preclinical animal studies, according to a new study in the journal npj Vaccines. San Antonio, Jan 28, 2022.- The research is a collaboration between Trudeau Institute, Texas Biomedical Research Institute’s Southwest NationalContinuar Leyendo
